“This again?!” Crossword Clue

 The crossword clue "This again?!" can have several answers, depending on the context. Here are a few possibilities:

Encore

Rerun

Repeat

Déjà vu

Groundhog Day

Rinse and repeat

Broken record

Been there, done that

Here we go again

Oh great

If you are looking for a more general answer, you could also say "repetition" or "reoccurrence."

Which answer is correct will depend on the other clues in the crossword puzzle and the overall theme. For example, if the puzzle has a theme related to music, then the answer is more likely to be "encore." If the puzzle is about television, then the answer is more likely to be "rerun."

I hope this helps!