Third-largest city of Colombia Crossword Clue

 The third-largest city in Colombia is Cali. It is the capital of the Valle del Cauca department and is located in the southwest of the country. The city has a population of over 2.4 million people and is known for its salsa music and culture.

The crossword clue "Third-largest city of Colombia" could be answered with the word CALI. This is a 4-letter word that is short and easy to remember, making it a good choice for a crossword clue. The word is also unique to Colombia, so it is unlikely to be confused with any other cities.

Here are some other possible answers for the crossword clue "Third-largest city of Colombia":

Barranquilla

Cartagena

Cúcuta

Medellín

Santa Marta

However, the most likely answer is CALI, as it is the third-largest city in Colombia.