Ham-and-cheese sandwich Crossword Clue

 The answer to the crossword clue "Ham-and-cheese sandwich" is CUBAN. It is a type of sandwich that originated in Cuba and is made with ham, Swiss cheese, pickles, and mustard. The bread is typically pressed and grilled, and the sandwich is often served hot.

Here are some other possible answers for the clue "Ham-and-cheese sandwich", depending on the difficulty of the puzzle:

SANDWICH (9 letters)

GRILLED (6 letters)

MEAL (4 letters)

I hope this helps!